Scorpion Cardiotoxicity

Scorpion Bite

Anthracycline Cardiotoxicity

In this issue, Gupta et al describe a novel mechanism, mediated through alterations in the RNA-binding protein QKI (Quaking), responsible for anthracycline-mediated cardiotoxicity. Performing global transcriptional profiling in murine hearts exposed to doxorubicin, they identified 5 differentially expressed RNA-binding proteins: 4 of which were upregulated and 1 QKI which was downregulated. QKI...

Effectiveness of anti scorpion venom for red scorpion envenomation.

OBJECTIVE To study the efficacy of anti-scorpion venom plus prazocin. METHODS Comparison of clinical features, outcome and duration of stay between children receiving anti-scorpion venom plus prazocin or prazocin alone for management of red scorpion envenomation. RESULTS Requirement for dopamine and requirement and duration of dobutamine therapy were significantly less in patients received ...

Anthracycline Cardiotoxicity

Anthracyclines remain an integral part of chemotherapy regimens in many adult and pediatric cancers but cause myocardial damage that may manifest as either subclinical decrements of left ventricular ejection function or overt cardiomyopathy. Anthracycline-related cardiotoxicity is doselimiting, and the risks of congestive heart failure increase with higher cumulative doses, particularly above 5...

Anthracycline cardiotoxicity.

Anthracyclines remain an integral part of chemotherapy regimens in many adult and pediatric cancers but cause myocardial damage that may manifest as either subclinical decrements of left ventricular ejection function or overt cardiomyopathy. Anthracycline-related cardiotoxicity is doselimiting, and the risks of congestive heart failure increase with higher cumulative doses, particularly above 5...